MORPHOLOGICAL CHANGES OF THE GALLBLADDER IN PATIENTS WITH CHRONIC CHOLECYSTITIS AND CHOLESTEROLOSIS DEPENDING ON COMORBID PATHOLOGY: CHD. CARDIOSCLEROSIS AND OBESITY

Objective – to study the morphological changes of gallbladder in patients with chroniccholecystitis and cholesterolosis depending on comorbid pathologycoronary heart disease (CHD) obesity. Materials methods. A retrospective analysis 300 autopsy protocols patientswith obesity, who died from complications CHD (group A) 100 ofpathohistological examination after cholecystectomy for obese B) has been carries out. The average age groupA was 67.3±5.24 years, group B 52.8±3.24 years. 157 preparations were studied bythe pathohistological method, stereometric selected histopreparationsof 112 cases biopsy cholecystectomy. Analysis ofthe state I-II degree obesity CHDwas performed according groups.Results. According data deceased CHD. Cardiosclerosiswith degree, features lesion GB(gallbladder)was comorbidity chronic cholecystitis: stones 24.3 %, nonstones 50.7 % cases, xanthogranulomatous cholecystitis observedin 1.7 patients. In 41.7 accompanying thegallbladder determined. Study gallbladderremoved during people Cardiosclerosis established presence cholecyctitis 100.0 cases:calculous prevailed 73.0 non-calculous accountedfor 20.0 7.0 patients, wasobserved. 57.0 an gallbladderwas determined: calculous 40.0 in17.0 a predominance reticular (64.9 %) form diffuse type (56.1 %), mixed(reticular- polypous) (24.6 polypous forms (10.5 %). Among CHD.Cardiosclerosis is more often observed women(3.2:1), also women inthe ratio men: 2.8:1. Morphological signs withCHD are probable thickening wall (in range 2.6-3.0times (p<0.05)), case concomitant 3.5-3.8times (р<0.05), biliary sludge (100.0 %).Сonclusions. coronary combined cholesterosis gallbladderoccur (3.2:1 2.8:1, respectively). ofgall bladders removed persons ischemic diseaseand indicate %of cases.